Nuevo Leon is also home of powerful conglomerates, such as Cemex (one of the largest construction materials firms in the world), Bimbo (bakery and pastry), Maseca (food and grains), Banorte (the only high-street bank in Mexico wholly owned by Mexicans), ALFA (Sigma, Alestra, Nemak, Alpek and Hylsa (recently bought by Ternium), i-service (HelpDesk), Vitro SA (glass), FEMSA (Coca-Cola in Latin America), and Cervecería Cuauhtémoc Moctezuma (brewers of Sol, Tecate, XX, Bohemia, Indio and Nochebuena).

As of 2010, Nuevo León's economy represents 11.4% of Mexico's total gross domestic product or US$165 billion. Nuevo León's economy has a strong focus on export oriented manufacturing. Foreign direct investment in Nuevo León was 1,213.1 million USD for 2005. In recent years, the state government has been making efforts in attracting significant investments in aeronautics, biotechnology, mechatronics, information and communication technologies fields with the creation of the Research and Technology Innovation Park PIIT (Parque de Investigación e Innovación Tecnológica), a technology park oriented in the development, innovation and research of sciences. The project is one of the key strategies within the Monterrey, City of Knowledge program.

GDP NUEVO LEON $105 557 million of USD