Southern Tamaulipas' economy is based primarily on the petrochemical industries. There are petrochemical production plants around Altamira as well as a principal Gulf coast container port, refinery facilities in Ciudad Madero and many oil-industry support service companies in Tampico, as well as a major general and bulk cargo port. Also of importance are the tourism and fishing industries, as well as much commercial shipping, based in Tampico and Altamira. The little village of La Pesca, in the municipality of Soto La Marina, about midway between Brownsville, Texas and Tampico, is a rapidly growing tourist area with lovely beaches and excellent fishing both in the Gulf of Mexico and the Rio Soto La Marina. The central zone contains the capital, Ciudad Victoria, and is home to much forestry and farming, as well as some industrial development. About 30% of the population lives here, both in the capital and in Ciudad Mante. Ciudad Victoria is a significant educational center, home to the Autonomous University of Tamaulipas (which also has campuses in other cities in the state), the Regional Technical Institute of Ciudad Victoria, the University of Valle de Bravo, and other institutions of learning.

As of 2005, Tamaulipas's economy represents 3.3% of Mexico's total gross domestic product or 21,664 million USD.Tamaulipas's economy has a strong focus on export oriented manufacturing. As of 2005, 258,762 people are employed in the manufacturing sector. Foreign direct investment in Tamaulipas was 386.2 million USD for 2005.

GDP TAMAULIPAS $39 629 millions of USD, comparable to Uruguay.